Search on:
ANTIGENS, CD137
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Antigens, CD137
Descriptor
Spanish
:
Antígenos CD137
Descriptor
Portuguese
:
Antígenos CD137
Synonyms
English
:
4-1BB Receptors
CD137 Antigens
Tumor Necrosis Factor Receptor Superfamily, Member 9
Tree Number:
D12.776.543.750.705.852.760.220
D23.050.301.264.035.237
D23.101.100.110.237
Definition
English
:
A member of the tumor
necrosis
factor receptor superfamily that is specific for
4-1BB LIGAND
. It is found in a variety of immune cell types including activated
T-LYMPHOCYTES
; NATURAL
KILLER CELLS
; and
DENDRITIC CELLS
. Activation of the receptor on
T-LYMPHOCYTES
plays a
role
in their expansion, production of
cytokines
and
survival
. Signaling by the activated receptor occurs through its
association
with TNF RECEPTOR-ASSOCIATED FACTORS.
History Note
English
:
2007(1993)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52384
Unique Identifier:
D053261
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS